Multiple apocrine poromas: a new case report.
Multiple apocrine poromas: a new case report.
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多发性顶浆孔瘤：一个新病例报告。
DOI：
10.1111/cup.12574
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发表时间：
2015
期刊：
影响因子：
1.7
通讯作者：
Nishigori C.
中科院分区：
文献类型：
--
作者：
Nishioka M;Kunisada M;Fujiwara N;Oka M;Funasaka Y;Nishigori C.
顶浆分泌汗孔瘤是一种罕见的良性附件肿瘤，其特征是肿瘤细胞向毛囊皮脂腺-顶浆分泌单位分化。我们报告一个极为罕见的情况下，多个顶浆汗孔瘤在一个单一的病人。1例74岁男性患者，15个肿瘤分布于头颈部、前臂和腋窝，肿瘤主要由多孔样细胞组成，周围有大小不等的导管间隙，部分有断头状分泌物。孔样细胞连续，具有漏斗样结构，含有成熟皮脂细胞的聚集体。患者无类似肿瘤家族史，无免疫抑制治疗史。这是第一次报道多发性顶浆汗孔瘤，提示易感遗传因素可能在肿瘤的发展中起作用。
Apocrine poromas are rare and distinctive benign adnexal neoplasms featuring tumor cells differentiating toward folliculosebaceous‐apocrine units. We report an extremely rare case with multiple apocrine poromas in a single patient. Fifteen tumors were distributed on the head, neck, forearm and axilla of a 74‐year‐old man. All tumors were mostly composed of poroid cells that surrounded variably sized duct spaces, some of which exhibited decapitation secretion. The poroid cells were continuous with infundibulum‐like structures that contained aggregates of mature sebocytes. The patient had no family history of similar tumors and no history of immunosuppressive therapy. This is the first report of multiple apocrine poromas, suggesting that predisposing genetic factors might play a part in the development of the tumors.