Free-Breathing High-Spatial-Resolution Delayed Contrast-Enhanced Three-Dimensional Viability MR Imaging of the Myocardium at 3.0T: A Feasibility Study
Free-Breathing High-Spatial-Resolution Delayed Contrast-Enhanced Three-Dimensional Viability MR Imaging of the Myocardium at 3.0T: A Feasibility Study
复制标题
DOI：
10.1002/jmri.21595
复制
发表时间：
2008-12-01
影响因子：
4.4
通讯作者：
Kumita, Shinichiro
中科院分区：
文献类型：
--
作者：
Amano, Yasuo;Matsumura, Yoshio;Kumita, Shinichiro
目的：评估 3.0T 自由呼吸高空间分辨率延迟对比增强三维 (3D) 活力磁共振成像 (MRI) 用于检测心肌损伤的可行性。 材料和方法：在知情同意后，纳入 25 名患有心肌疾病（包括心肌梗死和心肌病）的患者。将 3.0T 下具有高空间分辨率 (1.5 x 1.25 x 2.5 mm) 的自由呼吸 3D 活力 MRI（采用心脏和导航门控技术）与屏气二维 (2D) 活力成像 (1.77 x 1.18 x 10 mm) 进行比较，以评估对比噪声比 (CNR) 和心肌损伤。 结果：自由呼吸 3D 活力25 名患者中有 21 名成功实现成像。该成像技术描绘了 84.6% 的超增强心肌，超增强心肌和血液之间的 CNR 较高，并且心肌损伤的透壁扩展具有极好的一致性 (k = 0.91)。特别是，3D 活力图像描绘了心肌梗死和线性超增强心肌，与 2D 活力图像相当。结论：使用 3.0T 的自由呼吸高空间分辨率延迟对比增强 3D 活力 MRI 对于评估超增强心肌是可行的。如心肌梗塞和心肌病所示。
Purpose: To assess the feasibility of free-breathing high-spatial-resolution delayed contrast-enhanced three-dimensional (3D) viability magnetic resonance imaging (MRI) at 3.0T for the detection of myocardial damages.Materials and Methods: Twenty-five patients with myocardial diseases, including myocardial infarction and cardiomyopathies, were enrolled after informed consent was given. Free-breathing 3D viability MRI with high spatial resolution (1.5 x 1.25 x 2.5 mm) at 3.0T, for which cardiac and navigator gating techniques were employed, was compared with breath-hold two-dimensional (2D) viability imaging (1.77 x 1.18 x 10 mm) for assessment of contrast-to-noise ratio (CNR) and myocardial damage.Results: Free-breathing 3D viability imaging was achieved successfully in 21 of the 25 patients. This imaging technique depicted 84.6% of hyperenhancing myocardium with a higher CNR between hyperenhancing myocardium and blood and with excellent agreement for the transmural extension of myocardial damage (k = 0.91). In particular, the 3D viability images delineated the myocardial infarction and linear hyperenhancing myocardium, comparable to the 2D viability images.Conclusion: Free-breathing high-spatial-resolution delayed contrast-enhanced 3D viability MRI using 3.0T was feasible for the evaluation of hyperenhancing myocardium. as seen with myocardial infarction and cardiomyopathies.