Empirical assessment of the factorial structure of clinical symptoms in schizophrenia - A multisite, multimodel evaluation of the factorial structure of the Positive and Negative Syndrome Scale
Empirical assessment of the factorial structure of clinical symptoms in schizophrenia - A multisite, multimodel evaluation of the factorial structure of the Positive and Negative Syndrome Scale
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DOI：
10.1159/000285058
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发表时间：
1997-09-01
期刊：
影响因子：
3.6
通讯作者：
Powchik, P
中科院分区：
文献类型：
--
作者：
White, L;Harvey, PD;Powchik, P
阳性和阴性症状量表（PANSS）被广泛用作精神分裂症症状评估的方法，但尚未确定症状如何构成的最完整模型。本研究使用验证性因素分析方法，对1，233名精神分裂症受试者的大样本进行了验证，检验了20个先前提出的模型的拟合优度。这些拟议的模型都不符合充分拟合经验数据的标准。然后对样本进行分层，一半的数据用于校准新模型。该模型在数据的后半部分得到验证。新的五角模型使用PANSS的30个项目中的25个，分为5个因素：积极，消极，焦虑情绪，激活和自闭症的关注。在年龄、严重程度和疾病慢性程度方面差异很大的患者在总体症状结构上没有差异。本研究的结果也暗示了一些问题的有效性PANSS目前配置时，用于评估精神分裂症的症状。
The Positive and Negative Syndrome Scale (PANSS) is widely used as a method for the assessment of symptoms of schizophrenia but the most complete model of how symptoms are structured has not been determined. Using the methods of confirmatory factor analysis with a large sample of 1,233 of schizophrenic subjects this study examined the goodness of fit of 20 previously proposed models. None of these proposed models met criteria for adequate fit to the empirical data. The sample was then stratified and half of the data was used to calibrate a new model. The model was validated in the second half of the data. The new pentagonal model uses 25 of the 30 items of the PANSS in 5 factors: positive, negative, dysphoric mood, activation, and and autistic preoccupation. Patients who varied widely in age, severity, and chronicity of illness did not differ in their overall symptom structure. The results of this study also implicated some problems in the validity of the PANSS as currently configured when used to assess symptoms of schizophrenia.