WHO WOULD HAVE THOUGHT IT - AN OPERATION PROVES TO BE THE MOST EFFECTIVE THERAPY FOR ADULT-ONSET DIABETES-MELLITUS
WHO WOULD HAVE THOUGHT IT - AN OPERATION PROVES TO BE THE MOST EFFECTIVE THERAPY FOR ADULT-ONSET DIABETES-MELLITUS
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DOI：
10.1097/00000658-199509000-00011
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发表时间：
1995-09-01
影响因子：
9
通讯作者：
DOHM, L
中科院分区：
文献类型：
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作者：
PORIES, WJ;SWANSON, MS;DOHM, L
背景资料众所周知，肥胖和糖尿病对药物治疗具有抵抗力，它们仍然是我们最常见和最严重的两种疾病。通过（1）将功能性胃减少到约30 mt，（2）用c. 0.8胃空肠Roux-en-Y吻合口40 ~ 60 cm。尽管许多患者病情严重，但手术的围手术期死亡率和并发症发生率分别为1.5%和8.5%。2018年10月17日，2018年10月17日，2018年10月17日，
ObjectiveThis report documents that the gastric bypass operation provides long-term control for obesity and diabetes.Summary Background DataObesity and diabetes, both notoriously resistant to medical therapy, continue to be two of our most common and serious diseases.MethodsOver the last 14 years, 608 morbidly obese patients underwent gastric bypass, an operation that restricts caloric intake by (1) reducing the functional stomach to approximately 30 mt, (2) delaying gastric emptying with a c. 0.8 to 1.0 cm gastric outlet, and (3) excluding foregut with a 40 to 60 cm Roux-en-Y gastrojejunostomy. Even though many of the patients were seriously ill, the operation was performed with a perioperative mortality and complication rate of 1.5% and 8.5%, respectively. Seventeen of the 608 patients (