The effect of chemical cleansing procedures combined with peracetic acid-ethanol sterilization on biomechanical properties of cortical bone
The effect of chemical cleansing procedures combined with peracetic acid-ethanol sterilization on biomechanical properties of cortical bone
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DOI：
10.1016/j.biologicals.2007.06.001
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发表时间：
2008-03-01
期刊：
影响因子：
1.7
通讯作者：
Suuronen, Riitta
中科院分区：
文献类型：
--
作者：
Haimi, Suvi;Vienonen, Annika;Suuronen, Riitta
过氧乙酸-乙醇灭菌（PES）是一种有效的同种异体骨灭菌方法，但其对骨生物力学性能的影响尚未见报道。本研究的目的是评估不同孵育时间的水，过氧化氢和酒精清洗程序结合PES对冻干皮质骨的生物力学性能的影响。通过对皮质样本进行三点弯曲试验，研究了这些影响。在机械测试之前，对冻干皮质样本进行再水化。与未处理的样品相比，经处理的皮质样品的弯曲强度和吸收能量略有增加，但杨氏模量降低。然而，当处理过的皮质样品的残留水分含量从
Peracetic acid-ethanol sterilization (PES) with a preceding delipidation step is an effective sterilization method for allograft bone, but its influence on biomechanical properties of bone has not been studied. The aim of this study was to evaluate the effects of different incubation times of water, hydrogen peroxide and alcohol cleansing procedures combined with PES on biomechanical properties of freeze-dried cortical bone. These effects were studied by performing three-point bending tests on cortical samples. The lyophilized cortical samples were rehydrated prior to mechanical testing. The bending strength and the absorbed energy of the processed cortical samples were increased slightly but the Young's modulus was decreased compared to unprocessed samples. However, when the residual moisture content of the processed cortical samples was reduced from