A cyclisation reaction of methyl (4R)-3-(2-diazo-3-oxobutanoyl)thiazolidine-4-carboxylate which proceeds with retention of configuration, probably via a planar ester enolate intermediate possessing axial chirality
A cyclisation reaction of methyl (4R)-3-(2-diazo-3-oxobutanoyl)thiazolidine-4-carboxylate which proceeds with retention of configuration, probably via a planar ester enolate intermediate possessing axial chirality
复制标题
(4R)-3-(2-重氮基-3-氧代丁酰基)噻唑烷-4-甲酸甲酯的环化反应，可能通过具有轴向手性的平面酯烯醇化物中间体进行，并保持构型
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
S. Vohra
中科院分区：
文献类型：
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作者：
B. Beagley;M. J. Betts;R. Pritchard;A. Schofield;R. J. Stoodley;S. Vohra
在基本条件下，标题化合物1b转化为甲基(6S)-3-乙酰基-2-氧-8-硫-1,4,5-三氮杂环[4.3.0]非3-烯-6-羧酸盐4a，通过x射线晶体学确定了其绝对构型。
Under basic conditions, the title compound 1b is converted into methyl (6S)-3-acetyl-2-oxo-8-thia-1,4,5-triazabicyclo[4.3.0]non-3-ene-6-carboxylate 4a, the absolute configuration of which is established by X-ray crystallography.