Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls

Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls
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DOI:
10.1210/jc.2002-021468
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发表时间:
2003-08-01
影响因子:
5.8
通讯作者:
Main, KM
Main, KM
中科院分区:
医学2区
文献类型:
--
作者:
Chellakooty, M;Schmidt, IM;Main, KM

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出生后早期对生殖激素的调节似乎在女孩中比在男孩中更为复杂。本研究的目的是描述473名3个月大的健康女婴中的促性腺激素A和B、FSH、LH、雌二醇和SHBG。在足月妊娠中,适合孕龄的女孩(n=355)的激素显示出明显的个体间差异,其浓度高达青春期值[中位数(95%置信区间):阿糖胞苷B,82 pg/ml(
The early postnatal regulation of reproductive hormones seems to be more complex in girls than in boys. The aim of this study was to describe inhibins A and B, FSH, LH, estradiol, and SHBG in a large prospective cohort of 473 unselected, healthy, 3-month-old girls. In full term, appropriate-for-gestational-age girls (n=355) hormones showed a marked interindividual variation, with concentrations up to pubertal values [medians (95% confidence intervals): inhibin B, 82 pg/ml (