Platelets, petechiae, and preservation of the vascular wall.
Platelets, petechiae, and preservation of the vascular wall.
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DOI：
10.1056/nejmra0800887
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发表时间：
2008-09-18
期刊：
影响因子：
--
通讯作者：
Rafii S
中科院分区：
文献类型：
--
作者：
Nachman RL;Rafii S
本文综述了血小板与内皮细胞之间的功能性接触，强调血小板释放的促血管生成细胞因子和生长因子对血管完整性的维持作用。这些分子与内皮细胞表面的受体结合，从而稳定血管内皮钙粘蛋白复合物。
This review concerns functional contacts between platelets and endothelial cells, with emphasis on the maintenance of vascular integrity by proangiogenic cytokines and growth factors released by platelets. These molecules bind to receptors on the surface of endothelial cells, thereby stabilizing the vascular-endothelium cadherin complex.