SINGLE UNIT RECORDING IN CAUDATE-NUCLEUS DURING SESSIONS WITH ELABORATE MOVEMENTS IN AWAKE MONKEY
SINGLE UNIT RECORDING IN CAUDATE-NUCLEUS DURING SESSIONS WITH ELABORATE MOVEMENTS IN AWAKE MONKEY
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DOI：
10.1016/0006-8993(74)90976-7
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发表时间：
1974-01-01
期刊：
影响因子：
2.9
通讯作者：
MEREAUX, J
中科院分区：
文献类型：
--
作者：
BUSER, P;POUDEROUX, G;MEREAUX, J
在清醒猕猴的尾状核进行单位记录。研究人员研究了三种动作：(A)从托盘中抓取固体食物(花生)并将其送到嘴里的自然大动作；(B)为获得液体奖励而进行的小幅度杠杆按压动作(果汁)，主要涉及远端节段(手指、手腕)；(C)与(B)相同，但主要涉及近端肌肉，包括用手臂和肩膀进行充分的等张拉动作。在上述每种动作之前和期间(但动物不同)，都记录了单位。结果表明：(1)尾状细胞在运动的不同阶段均被加速；(2)在(A)和(B)两种情况下激活的细胞多于(C)；(3)极少数细胞表现为抑制而不是兴奋；(4)在运动过程中改变的细胞中，极少数细胞也被被动的前肢屈曲或伸展加速；(5)一些尾状细胞也被各种视觉或听觉并发刺激明显激活，可能引起动物的注意。
Unit recordings were performed in the caudate nucleus of awake macaques. Animals were maintained in a restraining chair and had been trained to perform various types of elaborate movements to obtain food-reward.Three types of movement were studied: (a) natural, large gestures of grasping solid food (peanut) from a tray and bringing it to the mouth; (b) small amplitude lever-pressing movements for fluid reward (fruit juice), mainly involving distal segments (fingers, wrist); (c) same as (b), but involving essentially proximal musculature, and consisting of an ample isotonic pulling with arm and shoulder.Units were recorded before and during each of the preceding types of movements (but in different animals). Results indicate that: (1) caudate cells were encountered in all 3 cases which were accelerated during different stages of the movement; (2) more cells were activated in situations (a) and (b) than (c); (3) very few cells displayed inhibition instead of excitation; (4) among cells modified during movement, very few were also accelerated through passive flexions or extensions of the forelimb; (5) some caudate cells were also clearly activated through various visual or auditory intercurrent stimuli, probably arousing the animal's attention.