Prevalence and factor analysis of metabolic syndrome in an urban Korean population
Prevalence and factor analysis of metabolic syndrome in an urban Korean population
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DOI：
10.2337/diacare.27.8.2027
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发表时间：
2004-08-01
期刊：
影响因子：
16.2
通讯作者：
Barrett-Connor, E
中科院分区：
文献类型：
--
作者：
On, JY;Hong, YS;Barrett-Connor, E
目的-本研究的目的是探讨的患病率和模式的代谢综合征及其与高胰岛素血症在韩国城市人口的269名男性和505 women.Research设计和方法-国家胆固醇教育计划成人治疗小组（ATP）III指南被用来计算性别特异性患病率的代谢综合征。在排除服用高血压、糖尿病或血脂异常药物的个体后，我们使用因子分析来检查206名男性和449名女性的代谢综合征模式。结果-代谢综合征的患病率在30-80岁的男性为16.0%，女性为10.7%。然而，ATP III中心性肥胖的标准对于亚太地区的人群并不是最佳的;当男性腰围从102 cm减少到90 cm，女性腰围从88 cm减少到80 cm时，代谢综合征的患病率分别增加到29.0%和16.8%。性别特异性因素分析显示，男性有4个因素（肥胖、葡萄糖耐受不良、高血压和血脂异常），女性有3个因素（肥胖-高血压、葡萄糖耐受不良和肥胖-血脂异常）。从空腹胰岛素水平估计的胰岛素抵抗与男性四个因素中的三个和女性三个因素中的两个聚集。ATP III或亚太腰围标准，代谢综合征的患病率增加，增加三分位数的胰岛素抵抗，这是估计由稳态模型assessment.CONCLUSIONS-代谢综合征是常见的韩国城市人口时，使用亚太腰围标准。代谢综合征的患病率随着胰岛素抵抗三分位数的增加而增加。
OBJECTIVE- The aim of this study was to explore the prevalence and pattern of the metabolic syndrome and its association with hyperinsulinemia in an urban Korean population of 269 men and 505 women.RESEARCH DESIGN AND METHODS- The National Cholesterol Education Program Adult Treatment Panel (ATP) III guidelines were used to calculate the sex-specific prevalence of the metabolic syndrome. After excluding individuals taking medication for hypertension, diabetes, or dyslipidemia, we used factor analysis to examine the pattern of the metabolic syndrome in 206 men and 449 women.RESULTS- The prevalence of metabolic syndrome was 16.0% in men and 10.7% in women aged 30-80 years. However, ATP III criteria for central obesity are not optimal for an Asian-Pacific population; when waist circumference is reduced from 102 to 90 cm in men and 88 to 80 cm in women, the prevalence of the metabolic syndrome increased to 29.0 and 16.8%, respectively. Sex-specific factor analysis showed four factors in men (obesity, glucose intolerance, hypertension, and dyslipidemia) and three in women (obesity-hypertension, glucose intolerance, and obesity-dyslipidemia). Insulin resistance estimated from fasting insulin levels clustered with three of the four factors in men and two of the three factors in women. By ATP III or Asian-Pacific waist circumference criteria, the prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance, which was estimated by a homeostasis model assessment.CONCLUSIONS- The metabolic syndrome is common in an urban Korean population when using Asian-Pacific waist criteria. The prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance.