Air Pollutants, Climate, and the Prevalence of Pediatric Asthma in Urban Areas of China.

Air Pollutants, Climate, and the Prevalence of Pediatric Asthma in Urban Areas of China.
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DOI:
10.1155/2016/2935163
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发表时间:
2016
影响因子:
--
通讯作者:
Wang Q
Wang Q
中科院分区:
生物学3区
文献类型:
--
作者:
Zhang J;Dai J;Yan L;Fu W;Yi J;Chen Y;Liu C;Xu D;Wang Q

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背景。儿童哮喘患病率在不同地区之间存在显着差异,但其原因尚不清楚,只有少数研究报告了这种差异的相关原因。客观的。调查城市平均空气污染物水平和气候因素的潜在作用,以区分中国哮喘患病率的差异并解释其原因。方法。第三次全国城市儿童哮喘调查涉及10,777名哮喘患者。同期空气污染物和其他气候因素的年平均浓度是从多个政府部门获得的。数据分析采用描述性统计、皮尔逊相关系数和多元回归分析。结果。 Pearson相关分析显示,儿童哮喘状况与SO2、相对湿度、日照时数密切相关(p < 0.05)。多元回归分析表明,在最后一步的预测变量中,SO2 被发现是最强大的预测变量(β = -19.572,p < 0.05)。此外,结果表明日照时数(β = -0.014,p < 0.05)是一个重要的汇总预测变量。结论。这项研究的结果并不表明空气污染物或气候(至少对于儿童而言)在解释中国哮喘患病率的区域差异方面发挥着重要作用。
Background. Prevalence of childhood asthma varies significantly among regions, while its reasons are not clear yet with only a few studies reporting relevant causes for this variation. Objective. To investigate the potential role of city-average levels of air pollutants and climatic factors in order to distinguish differences in asthma prevalence in China and explain their reasons. Methods. Data pertaining to 10,777 asthmatic patients were obtained from the third nationwide survey of childhood asthma in China's urban areas. Annual mean concentrations of air pollutants and other climatic factors were obtained for the same period from several government departments. Data analysis was implemented with descriptive statistics, Pearson correlation coefficient, and multiple regression analysis. Results. Pearson correlation analysis showed that the situation of childhood asthma was strongly linked with SO2, relative humidity, and hours of sunshine (p < 0.05). Multiple regression analysis indicated that, among the predictor variables in the final step, SO2 was found to be the most powerful predictor variable amongst all (β = −19.572, p < 0.05). Furthermore, results had shown that hours of sunshine (β = −0.014, p < 0.05) was a significant component summary predictor variable. Conclusion. The findings of this study do not suggest that air pollutants or climate, at least in terms of children, plays a major role in explaining regional differences in asthma prevalence in China.