Membranes of the world unite!

Membranes of the world unite!
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DOI:
10.1083/jcb.200607083
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发表时间:
2006-10-23
影响因子:
7.8
通讯作者:
Kozlov, Michael M
Kozlov, Michael M
中科院分区:
生物学1区
文献类型:
--
作者:
Chernomordik, Leonid V;Zimmerberg, Joshua;Kozlov, Michael M

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尽管起源不同,但细胞融合机制集中在磷脂双层融合途径。在这篇简短的综述中,我们讨论了蛋白质如何介导融合途径中的三个主要阶段:接触,半融合和扩大融合孔的开放。
Despite diverse origins, cellular fusion mechanisms converge at a pathway of phospholipid bilayer fusion. In this mini-review, we discuss how proteins can mediate each of the three major stages in the fusion pathway: contact, hemifusion, and the opening of an expanding fusion pore.