A fast microfluidic mixer based on acoustically driven sidewall-trapped microbubbles
A fast microfluidic mixer based on acoustically driven sidewall-trapped microbubbles
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DOI：
10.1007/s10404-009-0444-3
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发表时间：
2009-11-01
影响因子：
2.8
通讯作者：
Huang, Tony Jun
中科院分区：
文献类型：
--
作者：
Ahmed, Daniel;Mao, Xiaole;Huang, Tony Jun
由于微尺度流体流动的低雷诺数，使得两种流体难以快速均匀混合。在这封信中，我们报告了一种通过使用基于气泡的微流控结构的快速均匀混合装置。这种微混合装置通过在通道侧壁上预先设计的凹槽内捕获气泡来工作。当声学驱动时，这些被困气泡的膜（液/气界面）开始振荡。气泡振荡导致了微流现象——散装液体中强烈的压力和速度波动，从而使两种并排流动的流体快速均匀混合。通过将去离子水和油墨以不同的流速混合，对混合器的性能进行了表征。混合时间可小至120毫秒。
Due to the low Reynolds number associated with microscale fluid flow, it is difficult to rapidly and homogenously mix two fluids. In this letter, we report a fast and homogenized mixing device through the use of a bubble-based microfluidic structure. This micromixing device worked by trapping air bubbles within the pre-designed grooves on the sidewalls of the channel. When acoustically driven, the membranes (liquid/air interfaces) of these trapped bubbles started to oscillate. The bubble oscillation resulted in a microstreaming phenomenon-strong pressure and velocity fluctuations in the bulk liquid, thus giving rise to fast and homogenized mixing of two side-by-side flowing fluids. The performance of the mixer was characterized by mixing deionized water and ink at different flow rates. The mixing time was measured to be as small as 120 ms.