Embracing complexity in biomaterials design.
Embracing complexity in biomaterials design.
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DOI：
10.1016/j.bbiosy.2022.100039
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发表时间：
2022-06
影响因子：
--
通讯作者：
Mata, Alvaro
中科院分区：
文献类型：
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作者：
Azevedo, Helena S;Mata, Alvaro
生物材料需要新的范式，以突破当前指导但也限制其设计的界限。拥抱生物材料设计的复杂性需要采用考虑系统级设计的整体方法。拥抱生物材料设计的复杂性将使新一代生物材料具有栩栩如生的特性，并将扩展其能力，从而在医疗领域释放新的范式。活性材料，即行为类似于生命系统的人造材料，吸引了从建筑、运输业到医药等一系列领域的巨大兴趣。在这篇主要观点文章中，我们提出，拥抱生物材料设计的复杂性提供了尚未开发的机会，可以创造具有创新的逼真特性的生物材料，从而扩展其功能并释放医疗治疗的新范式。
There is a need for new paradigms in biomaterials that can push the current boundaries that guide, yet also limit, their design. Embracing complexity in biomaterials design will require an holistic approach that considers a systems-level design. Embracing complexity in biomaterials design will enable a new generation of biomaterials with life-like properties and will extend their capabilities to unleash new paradigms in medical treatment. Animate materials, man-made materials behaving like living systems, are attracting enormous interest across a range of sectors, from construction and transport industry to medicine. In this leading opinion article, we propose that embracing complexity in biomaterials design offers untapped opportunities to create biomaterials with innovative life-like properties that extend their capabilities and unleash new paradigms in medical treatment.