JSNP: a database of common gene variations in the Japanese population
JSNP: a database of common gene variations in the Japanese population
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DOI：
10.1093/nar/30.1.158
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发表时间：
2002-01-01
影响因子：
14.9
通讯作者：
Nakamura, Y
中科院分区：
文献类型：
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作者：
Hirakawa, M;Tanaka, T;Nakamura, Y
JSNP是日本单核苷酸多态(SNP)数据的储存库，始于2000年，是通过首相的千禧年项目开发的。这项工作的目的是从日本人群中识别和核对多达15万个SNPs，这些SNPs位于可能影响基因编码序列的基因或邻近区域。该项目由东京大学医学科学研究所(IMS)的人类基因组中心(HGC)和日本科学技术公司(JST)合作实施。JSNP既是从正在进行的项目中获得的日本SNP的存储地点，也是使研究人员能够获得高质量SNP数据的公共传播设施。该项目的一个主要动机是建立一个基本数据集，以确定多态与常见疾病或药物反应之间的关系。因此，重点是识别位于候选区域的SNPs，这些区域可能影响表型，但不一定会直接导致疾病。在http://snp.ims.u-tokyo.ac.jp/.上可以不受限制地访问JSNP和任何相关文件
JSNP is a repository of Japanese Single Nucleotide Polymorphism (SNP) data, begun in 2000 and developed through the Prime Minister's Millennium Project. The aim of this undertaking is to identify and collate up to 150 000 SNPs from the Japanese population, located in genes or in adjacent regions that might influence the coding sequence of the genes. The project has been carried out by a collaboration between the Human Genome Center (HGC) in the Institute of Medical Science (IMS) at the University of Tokyo and the Japan Science and Technology Corporation (JST). JSNP serves as both a storage site for the Japanese SNPs obtained from the ongoing project and as a facility for public dissemination to allow researchers access to high quality SNP data. A primary motivation of the project is the construction of a basic data set to identify relationships between polymorphisms and common diseases or the reaction to drugs. As such, emphasis has been placed on the identification of SNPs that lie in candidate regions which may affect phenotype but which would not necessarily directly cause disease. Unrestricted access to JSNP and any associated files is available at http://snp.ims.u-tokyo.ac.jp/.