Child and Adolescent Depression Intervention Overview: What Works, for Whom and How Well?
Child and Adolescent Depression Intervention Overview: What Works, for Whom and How Well?
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DOI：
10.1016/j.chc.2012.01.001
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发表时间：
2012-04-01
影响因子：
2.4
通讯作者：
Brent, David A.
中科院分区：
文献类型：
--
作者：
Maalouf, Fadi T.;Brent, David A.
作者回顾了目前儿童和青少年重性抑郁障碍的循证治疗。单药治疗，即选择性5-羟色胺再摄取抑制剂，得到了青少年大型临床试验的支持。对于轻中度抑郁症，认知行为疗法（CBT）和人际关系疗法是合理的选择。也有证据表明，药物和CBT的组合是上级优于单独药物治疗的速度加快治疗反应和缓解，尽管一些负面的研究。急性治疗后和长期随访期间的反应，缓解和复发率也进行了介绍和讨论。
The authors review the currently available evidence-based treatments of child and adolescent major depressive disorder. Medication monotherapy, namely with selective serotonin reuptake inhibitors, is supported by large clinical trials in adolescents. For mild to moderate depression, cognitive behavior therapy (CBT) and interpersonal therapy are reasonable options as monotherapies. There is also evidence that the combination of medication and CBT is superior to medication alone for accelerating the pace of treatment response and remission, despite some negative studies. Response, remission, and recurrence rates after acute treatment and during long-term follow-ups are also presented and discussed.