Chorioamnionitis and early pregnancy loss caused by ampicillin-resistant non-typeable Haemophilus influenzae
Chorioamnionitis and early pregnancy loss caused by ampicillin-resistant non-typeable Haemophilus influenzae
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耐氨苄青霉素不可分型流感嗜血杆菌引起的绒毛膜羊膜炎和早期妊娠流产
DOI：
10.1016/j.idcr.2023.e01751
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发表时间：
2023
期刊：
影响因子：
1.5
通讯作者：
Kasahara Kei
中科院分区：
文献类型：
--
作者：
Nishihara Yuji;Hirai Nobuyasu;Sekine Takahiro;Okuda Nao;Nishimura Tomoko;Fujikura Hiroyuki;Furukawa Ryutaro;Imakita Natsuko;Fukumori Tatsuya;Ogawa Taku;Suzuki Yuki;Nakano Ryuichi;Nakano Akiyo;Yano Hisakazu;Kasahara Kei
流感嗜血杆菌可引起羊膜内感染和早期流产。探讨了H.子宫腔感染是未知的。在这里，我们提出的情况下，绒毛膜炎引起的氨苄青霉素耐药。一名32岁的日本妇女在怀孕16周时感染流感。尽管根据现行指南的建议进行了经验性治疗，包括氨苄青霉素，但她仍发生了胎儿丢失。抗生素方案改为头孢曲松，治疗完成，无并发症。虽然氨苄青霉素耐药引起的绒毛膜炎的患病率和危险因素。流感是未知的，临床医生需要认识到H。流感是一种对孕妇具有潜在抗药性和致命性的细菌。
Haemophilus influenzaecan cause intra-amniotic infection and early pregnancy loss. The mode of transmission and risk factors forH. influenzaeuterine cavity infections are unknown. Here, we present the case of chorioamnionitis caused by ampicillin-resistantH. influenzaein a 32-year-old Japanese woman at 16 weeks of gestation. Despite empirical treatment, including ampicillin, as recommended by the current guidelines, she had fetal loss. The antimicrobial regimen was changed to ceftriaxone, and the treatment was completed without complications. Although the prevalence and risk factors for chorioamnionitis caused by ampicillin-resistantH. influenzaeare unknown, clinicians need to recognizeH. influenzaeas a potentially drug-resistant and lethal bacterium for pregnant women.