Uniaxial and biaxial mechanical behavior of human amnion
Uniaxial and biaxial mechanical behavior of human amnion
复制标题
人类羊膜的单轴和双轴力学行为
DOI：
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
D. Landers
中科院分区：
文献类型：
--
作者：
M. Oyen;R. Cook;T. Stylianopoulos;V. Barocas;S. Calvin;D. Landers
绒毛膜是妊娠期间包裹胎儿的膜，是一种结构软组织，对维持妊娠和分娩的成功至关重要。然而，人们对这种组织膜的力学行为知之甚少。绒毛膜的结构成分是羊膜亚层，它通过致密的胶原网络提供膜的机械完整性，是本研究的重点。采用循环加载和应力松弛法进行羊膜单轴和平面等双轴拉伸试验。循环试验表明，在第一个循环中能量耗散剧烈，随后的循环中迟滞较小。每个循环的能量耗散分数与应变有关，在小应变水平下耗散最大。应力松弛测试显示出水平依赖的反应，并且在长时间的松弛后持续松弛。非线性粘弹性（可分离）遗传积分方法不适合模拟羊膜响应，因为应变和时间相关响应的内在耦合。
Chorioamnion, the membrane surrounding a fetus during gestation, is a structural soft tissue critical for maintaining a successful pregnancy and delivery. However, the mechanical behavior of this tissue membrane is poorly understood. The structural component of chorioamnion is the amnion sublayer, which provides the membrane’s mechanical integrity via a dense collagen network and is the focus of this investigation. Amnion uniaxial and planar equi-biaxial tension testing was performed using cyclic loading and stress-relaxation. Cyclic testing demonstrated dramatic energy dissipation in the first cycle followed by less hysteresis on subsequent cycles. Fractional energy dissipation per cycle was strain dependent, with greatest dissipation at small strain levels. Stress-relaxation testing demonstrated a level-dependent response and continued relaxation after long relaxation times. A nonlinear viscoelastic (separable) hereditary integral approach was inadequate to model the amnion response due to intrinsic coupling of the strain- and time-dependent responses.
人类脐静脉和羊水压力的正常值及其因胎儿疾病而改变。
影响因子：
9.8
作者：
Weiner,CP;Heilskov,J;Pelzer,G;Grant,S;Wenstrom,K;Williamson,RA
通讯作者：
Williamson,RA