ATP-binding cassette transporter A1: key player in cardiovascular and metabolic disease at local and systemic level.
ATP-binding cassette transporter A1: key player in cardiovascular and metabolic disease at local and systemic level.
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DOI：
10.1097/mol.0000000000000088
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发表时间：
2014-08
影响因子：
4.4
通讯作者：
M. Eck
中科院分区：
文献类型：
--
作者：
M. Eck
目的：三磷酸腺苷结合盒转运体A1(ABCA1)促进细胞胆固醇外流至低脂载脂蛋白AI(ApoAI)，在高密度脂蛋白的形成和功能中起关键作用。本文综述了ABCA1在心血管和Meta中作用的研究进展和新的见解。
Purpose of reviewATP-binding cassette transporter A1 (ABCA1) facilitates cellular cholesterol efflux to lipid-poor apolipoprotein AI (apoAI) and plays a key role in the formation and function of HDL. This review summarizes the advances and new insights in the role of ABCA1 in cardiovascular and meta