RHODOPSIN CONTENT AND ROD OUTER SEGMENT LENGTH IN ALBINO-RAT EYES - MODIFICATION BY DARK-ADAPTATION
RHODOPSIN CONTENT AND ROD OUTER SEGMENT LENGTH IN ALBINO-RAT EYES - MODIFICATION BY DARK-ADAPTATION
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DOI：
10.1016/0014-4835(78)90134-3
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发表时间：
1978-01-01
影响因子：
3.4
通讯作者：
LAVAIL, MM
中科院分区：
文献类型：
--
作者：
BATTELLE, BA;LAVAIL, MM
在不同的黑暗适应期、黑暗饲养期和循环光维持期后，测定了白化大鼠全眼视紫红质含量和视杆外段长度。深色饲养的白化大鼠眼睛中的视紫红质含量比循环光照（笼内照度小于15 ft-cd）下饲养的幼崽眼睛中的视紫红质含量高出约50%。白化大鼠仅在10天的黑暗适应期后，视紫红质的增加也相同。增加的视紫红质水平与在循环光照下饲养的有色素的大鼠的眼睛相同。白化大鼠眼睛中视紫红质含量的增加至少部分是由于视杆外段长度的增加。白化大鼠眼睛中视紫红质含量的增加至少部分是由于视杆外段长度的增加。暗适应和暗饲养对长度的增加有一定的影响，平均增加约25%。未发现杆外段直径、杆外段圆盘堆积密度或眼大小明显增加[电镜观察]。在适应黑暗的白化大鼠和处于循环光照下的色素沉着大鼠中，上半球的视杆外段长度始终比下半球长，而在循环光照下维持的白化大鼠中则不是这样。
Whole eye rhodopsin content and rod outer segment length were determined in albino rat eyes after different periods of dark adaptation, dark-rearing or cyclic light maintenance. The rhodopsin content in the eyes of dark-reared albino rats was approximately 50% higher than that in the eyes of littermates reared in cyclic light (in-cage illumination less than 15 ft-cd). The same increase in rhodopsin could be obtained in albino rats after only a 10 day dark adaptation period. The increased level of rhodopsin was the same as that in the eyes of pigmented rats reared in cyclic light. The increase in rhodopsin content in the albino rat eyes was due at least in part to an increase in rod outer segment length. The increase in rhodopsin content in the albino rat eyes was due at least in part to an increase in rod outer segment length. The increase in length with dark adaptation and dark-rearing was somewhat variable, with an average increase of approximately 25%. No apparent increase was found in rod outer segment diameter, rod outer segment disc packing density or eye size [as seen by EM]. Rod outer segment lengths were consistently longer in the superior hemisphere of the eye than in the inferior hemisphere in dark-adapted albino rats and pigmented rats maintained in cyclic light, but not in albino rats maintained in cyclic light.