Chemoreceptors in autonomic responses to hypoxia in conscious rats.

Chemoreceptors in autonomic responses to hypoxia in conscious rats.
复制标题

清醒大鼠对缺氧的自主反应中的化学感受器。

DOI:
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发表时间:
1996
影响因子:
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通讯作者:
M. Maeda
M. Maeda
中科院分区:
医学4区
文献类型:
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作者:
Y. Hayashida;H. Hirakawa;T. Nakamura;M. Maeda

文献摘要

被引文献

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有人认为,心血管对缺氧的反应是自主神经系统的影响与缺氧对中枢神经系统(CNS)和心血管系统的直接影响之间的综合相互作用而产生的(Daly,1986;Marshall,1994)。然而,在许多作品中,低氧暴露在达到稳定状态之前的时间相对较短。因此,这种反应可能是在综合互动开始运作之前就产生的。也没有关于清醒动物缺氧期间自主神经活动行为的信息,这可能与综合功能的研究相关。在这项研究中,检查了化学感受器完整的和去神经清醒的大鼠对全身缺氧的心血管反应期间的自主神经活动,以确定动脉化学感受器对这些反应的贡献。
It has been suggested that the cardiovascular responses to hypoxia are produced as integrated interactions between the effects of the autonomic nervous system and the direct effect of hypoxia on the central nervous system (CNS) and the cardiovascular system (Daly, 1986; Marshall, 1994). However, hypoxic exposure has been delivered for relatively short periods of time before attaining a steady state in many works. Therefore, such responses may have resulted before integrated interactions began operating. There is also no information on the behavior of the autonomic nervous activities during hypoxia in conscious animals, which may be relevant to the study of an integrated function. In this study, the autonomic nervous activities are examined during the cardiovascular responses of the chemoreceptor-intact and of denervated conscious rats to systemic hypoxia, in order to determine the contribution of the arterial chemoreceptors to these responses.