MAMMARY FIBROADENOMA WITH MULTINUCLEATED STROMAL GIANT-CELLS

MAMMARY FIBROADENOMA WITH MULTINUCLEATED STROMAL GIANT-CELLS
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DOI:
10.1097/00000478-198611000-00010
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发表时间:
1986-11-01
影响因子:
5.6
通讯作者:
CLEMENT, PB
CLEMENT, PB
中科院分区:
医学1区
文献类型:
--
作者:
BEREAN, K;TRON, VA;CLEMENT, PB

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我们研究了一位42岁女性的典型乳腺纤维腺瘤,在该瘤中,大量的、奇怪的、核分裂不活跃的、多核的巨细胞存在于整个间质中。免疫组织化学和超微结构研究证实了巨细胞的间质,特别是成纤维细胞的性质。这种类型的细胞通常是乳腺小叶间质中的偶发发现,是良性的,镜检时不应误认为是恶性细胞。
We have studied an otherwise typical mammary fibroadenoma in a 42-year-old female in which numerous, bizarre, mitotically inactive, multinucleated giant cells were present throughout the stroma. Immunohistochemical and ultrastructural studies confirmed the mesenchymal, specifically fibroblastic, nature of the giant cells. Cells of this type, which are more commonly an incidental finding within the interlobular stroma of the breast, are benign, and should not be mistaken for malignant cells on microscopic examination.