Respiration Rate, Heart Rate, and Body Temperature Values in Cynomolgus Monkeys (Macaca fascicularis) During Barbiturate Anesthesia
Respiration Rate, Heart Rate, and Body Temperature Values in Cynomolgus Monkeys (Macaca fascicularis) During Barbiturate Anesthesia
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巴比妥麻醉期间食蟹猴（食蟹猴）的呼吸频率、心率和体温值
DOI：
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发表时间：
1986
影响因子：
0.7
通讯作者：
Carol Micheletti
中科院分区：
文献类型：
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作者：
S. Zola;Carol Micheletti
对14只食蟹猴（Macaca fascularis）在巴比妥酸盐麻醉下进行神经外科手术时的呼吸速率、心率和体温进行了测定。生命体征值在手术早期明显下降到基线以下，随着手术的进展和接近完成而稳步上升，并最终在术后恢复期结束时恢复到基线。这14只猴子之间存在相当大的差异，但在整个观察期间，每只猴子相对于其他猴子的排名保持不变。研究结果表明，食蟹猴对巴比妥类药物的敏感性可能高于恒河猴，食蟹猴对巴比妥类药物的敏感性可能表现出相当大的个体差异。
Respiration rate, heart rate, and body temperature values were obtained from 14 cynomolgus monkeys (Macaca fascicularis) during neurosurgery under barbiturate anesthesia. Vital sign values markedly declined below baseline during the early stages of surgery, steadily increased as surgery progressed and neared completion, and finally returned to baseline by the end of the postsurgical recovery period. There was considerable variability among the 14 monkeys, but the ranking of each monkey relative to the others remained constant across the period of observation. The findings suggested that the cynomolgus monkey may be more sensitive to barbiturates than the rhesus monkey, and cynomolgus monkeys may exhibit considerable individual differences in their sensitivity to barbiturates.