Diagnostic rate of autism spectrum disorder in a high-survival cohort of children born very preterm: A cross-sectional study
Diagnostic rate of autism spectrum disorder in a high-survival cohort of children born very preterm: A cross-sectional study
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早产儿高存活率队列中自闭症谱系障碍的诊断率：一项横断面研究
DOI：
10.1002/jdn.10168
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
O.
中科院分区：
文献类型：
--
作者：
Nagai;Y.;Mizutani;Y.;Nomura;K.;Uemura;O.;Saitoh;S.;& Iwata;O.
为探讨早产儿高存活率群体中自闭症谱系障碍的诊断率，采用自闭症诊断观察表第2版和《精神障碍诊断与统计手册》第5版( -5)对77名早产儿(孕32周)在4-6岁时进行了评估。16名儿童(20.8%)同时被归类为DSM-5阳性的ASD和ADOS-2-被识别的“自闭症”，这在本研究中被定义为确诊的ASD。我们的结果表明，当对所有儿童进行单独评估时，极早产儿ASD的患病率可能比之前的研究报告的要高得多。需要在大样本中进行进一步的研究，以澄清早产中ASD的真实风险。
To investigate the diagnostic rate of autism spectrum disorder (ASD) in a high‐survival cohort of very preterm children, 77 infants born very preterm (<32 weeks of gestation) were assessed at age 4–6 years old using the Autism Diagnostic Observation Schedule, 2nd edition (ADOS‐2) and the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM‐5). Sixteen children (20.8%) were classified as both DSM‐5‐positive ASD and ADOS‐2‐identified “autism,” which were defined as confirmed ASD in this study. Our result suggests that the prevalence of ASD in very preterm children might be much higher than reported in previous studies when all children were individually evaluated. Further studies in a large sample are required to clarify the true risk of ASD in preterm birth.