Selection in a subdivided population with dominance or local frequency dependence.
Selection in a subdivided population with dominance or local frequency dependence.
复制标题
在具有优势或局部频率依赖性的细分群体中进行选择。
DOI：
10.1534/genetics.106.063636
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发表时间：
2003
期刊：
影响因子：
3.3
通讯作者：
J. L. Cherry
中科院分区：
文献类型：
--
作者：
J. L. Cherry
种群结构和自然选择之间的相互作用是一个非常有趣的领域。已知某些类型的种群细分在基因频率无关选择下不会改变所选等位基因的固定概率。在存在适合度优势或频率依赖选择的情况下，这些相同类型的细分对固定概率有很大的影响。例如，由于欠显性导致的更适合等位基因的固定障碍通过细分而减少。本文给出的分析结果将符合有限岛模型的细分种群与近似等效的泛型种群联系起来。这个等效人口的规模不同于（大于）细分人口的实际规模。在假设的等效种群中，选择参数也不同。正如预期的那样，在同等人群中，优势程度较低。结果不限于优势，但涵盖任何形式的多项式频率依赖。
The interplay between population structure and natural selection is an area of great interest. It is known that certain types of population subdivision do not alter fixation probabilities of selected alleles under genic, frequency-independent selection. In the presence of dominance for fitness or frequency-dependent selection these same types of subdivision can have large effects on fixation probabilities. For example, the barrier to fixation of a fitter allele due to underdominance is reduced by subdivision. Analytic results presented here relate a subdivided population that conforms to a finite island model to an approximately equivalent panmictic population. The size of this equivalent population is different from (larger than) the actual size of the subdivided population. Selection parameters are also different in the hypothetical equivalent population. As expected, the degree of dominance is lower in the equivalent population. The results are not limited to dominance but cover any form of polynomial frequency dependence.
中性基因的谱系和地理结构人群中选定突变的传播。
影响因子：
3.3
作者：
Takahata,N
通讯作者：
Takahata,N