CUMULATIVE EFFECTS OF SLEEP RESTRICTION ON DAYTIME SLEEPINESS
CUMULATIVE EFFECTS OF SLEEP RESTRICTION ON DAYTIME SLEEPINESS
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DOI：
10.1111/j.1469-8986.1981.tb02921.x
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发表时间：
1981-01-01
期刊：
影响因子：
3.7
通讯作者：
DEMENT, WC
中科院分区：
文献类型：
--
作者：
CARSKADON, MA;DEMENT, WC
在10名年轻的成年人受试者中评估睡眠和白天嗜睡，以确定恒定量的夜间睡眠限制是否会产生累积损害。受试者连续研究12天，包括3个基线日（卧床10小时）、7个睡眠限制为5小时的日和2个恢复日。在5例受试者中，恢复包括卧床10小时;在其余受试者中，恢复包括卧床5小时，白天小睡1小时。使用2个自评量表和多次睡眠潜伏期测试来测量嗜睡。在睡眠限制期间，夜间第2阶段和REM（快速眼动）睡眠减少，慢波睡眠不受影响。斯坦福大学嗜睡量表显示白天嗜睡立即增加，4天后达到平台。模拟嗜睡评定量表显示，2个限制性夜晚后嗜睡增加，第4个限制性夜晚后稳定。多次睡眠潜伏期测试显示，睡眠限制直到第2天才产生影响，随后嗜睡程度逐渐增加，持续到第7天。在恢复期间，在1个完整的夜晚睡眠后，白天嗜睡在所有3个测量值上都恢复到基础值;在白天小睡的情况下，没有观察到睡眠限制的进一步累积效应。
Sleep and daytime sleepiness were evaluated in 10 young adult human subjects to determine whether restricting nocturnal sleep by a constant amount produces cumulative impairment. Subjects were studied for 12 consecutive days, including 3 baseline days with a 10 h time in bed, 7 days with sleep restricted to 5 h and 2 recovery days. In 5 subjects, recovery included a 10 h time in bed; in the remaining subjects, recovery included a 5 h time in bed with a 1 h daytime nap. Sleepiness was measured using 2 self-rating scales and the multiple sleep latency test. During sleep restriction, nocturnal stage 2 and REM (rapid eye movement) sleep were reduced and slow wave sleep was unaffected. Stanford Sleepiness Scales showed an immediate increase in daytime sleepiness that reached a plateau after 4 days. An analog sleepiness rating scale showed increased sleepiness after 2 restricted nights and leveled off after the 4th restricted night. The multiple sleep latency tests showed no effect of sleep restriction until the 2nd day, followed by a progressive increase in sleepiness that persisted through the 7th sleep restriction day. During the recovery period, daytime sleepiness returned to basal values on all 3 measures following 1 full night of sleep; with a daytime nap, no further cumulative effects of sleep restriction were seen.