A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption.
A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption.
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发表时间：
1990-02
期刊：
影响因子：
11.2
通讯作者：
A. Nomura;John S. Grove;G. Stemmermann;Richard K. Severson
中科院分区：
文献类型：
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作者：
A. Nomura;John S. Grove;G. Stemmermann;Richard K. Severson
从1965年到1968年，在夏威夷，7990名日裔美国男性接受了一项队列研究的采访和检查。根据24小时饮食回忆史，记录食物频率问卷中20种不同食物的摄入量以及碳水化合物和其他营养素的摄入量。自那时以来，已发现150例胃癌病例。虽然胃癌患者（病例）比没有癌症的男性（非病例）更经常食用泡菜和火腿/培根/香肠，水果和油炸蔬菜更少，但没有统计学差异。与不吸烟者相比，目前吸烟者的风险增加（相对风险= 2.7; 95%置信区间= 1.8至4.1），但吸烟量较大时无剂量反应效应。饮酒，无论是啤酒、烈酒还是葡萄酒，都不会影响胃癌的发病率。在这项研究中未能检测到与膳食食物的关联可能是由于问卷中遗漏了许多东方食物以及24小时饮食回忆史的局限性。
From 1965 to 1968 in Hawaii, 7990 American men of Japanese ancestry were interviewed and examined in a cohort study. The intake of 20 separate foods in a food frequency questionnaire and the intake of carbohydrate and other nutrients, based on a 24-h diet recall history, were recorded. Since then, 150 incident cases of stomach cancer have been identified. Although men with stomach cancer (cases) consumed pickles and ham/bacon/sausages more often and fruits and fried vegetables less often than men without cancer (noncases), none of the differences was statistically significant. Current cigarette smokers had an increased risk (relative risk = 2.7; 95% confidence interval = 1.8 to 4.1) compared with nonsmokers, but there was no dose-response effect with heavier cigarette smoking. The consumption of alcohol, either from beer, spirits, or wine, did not affect the incidence of stomach cancer. The failure to detect an association with dietary foods in this study may be due to the omission of many oriental foods in the questionnaire and the limitations of the 24-h diet recall history.