Ligand-Promoted Borylation of C(sp(3))-H Bonds with Palladium(II) Catalysts.
Ligand-Promoted Borylation of C(sp(3))-H Bonds with Palladium(II) Catalysts.
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DOI：
10.1002/anie.201509996
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发表时间：
2016-01-11
期刊：
影响因子：
--
通讯作者：
Yu JQ
中科院分区：
文献类型：
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作者：
He J;Jiang H;Takise R;Zhu RY;Chen G;Dai HX;Dhar TG;Shi J;Zhang H;Cheng PT;Yu JQ
发现了一种喹啉基配体，可以有效地促进pd催化的C(sp3) -H键的硼化。羧酸衍生物中的初级β-C(sp3) -H键以及各种碳环（包括环丙烷、环丁烷、环戊烷、环己烷和环庚烷）中的次级C(sp3) -H键被硼化。这种定向硼化方法在范围和操作条件上补充了现有的Ir(I)和Rh(I)催化的C-H硼化反应。
A quinoline-based ligand is identified to effectively promote Pd-catalyzed borylation of C(sp3)–H bonds. Primary β-C(sp3)–H bonds in carboxylic acid derivatives as well as secondary C(sp3)–H bonds in a variety of carbocyclic rings including cyclopropanes, cyclobutanes, cyclopentanes, cyclohexanes, and cycloheptanes are borylated. This directed borylation method complements existing Ir(I) and Rh(I)-catalyzed C–H borylation reactions in terms of scope and operational conditions.