Uncertainty analysis of chest X-ray lung height measurements and size matching for lung transplantation.
Uncertainty analysis of chest X-ray lung height measurements and size matching for lung transplantation.
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胸部X射线肺高度测量和肺移植的尺寸匹配的不确定性分析。
DOI：
10.21037/jtd-21-1755
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发表时间：
2022-04
影响因子：
2.5
通讯作者：
Trulock, Elbert P.
中科院分区：
文献类型：
--
作者：
Guillamet, Rodrigo Vazquez;Guillamet, Maria C. Vazquez;Rjob, Ashraf;Bierhals, Andrew;Bello, Irene;Abularach, Alberto Jauregui;Tague, Laneshia;Wallendorf, Michael;Marklin, Gary F.;Witt, Chad;Byers, Derek E.;Kreisel, Daniel;Nava, Ruben;Puri, Varun;Hachem, Ramsey;Trulock, Elbert P.
测量胸片（CXR）肺高度的错误可能导致肺移植手术尺寸不匹配的发生。我们首先使用Bland-Altman分析对重复测量进行评估，以评估胸片肺高度测量误差的影响因素。然后我们应用误差传播理论来评估测量误差对肺移植尺寸匹配的影响。共有387张来自25位捐赠者和25位接受者的胸部x光片由两名评分员进行测量。肺高度差异的个体标准偏差与年龄、性别、供体与受体、诊断组和种族/民族无关，所有这些都被汇总用于分析。评分者对左右肺的偏差分别为0.27 cm（±0.03）和0.22 cm（±0.06）。受试者的变异是测量误差的最大因素，左右肺高度分别为2.76 cm（±0.06）和2.78 cm（±0.2）。必须接受供体和受体右肺高度之间4.4 cm或以上的高度差（95% CI：±4.2，±4.6 cm），以确保至少95%的患者具有相同的真实肺高度。当使用所有可用的胸部x光片的平均值时，这种差异减小到±1.1厘米（95% CI：±0.9，±1.3厘米）。供体与受体匹配的概率随着真实肺高差的增加而降低。在肺移植手术中，个体胸片肺高度不精确。平均胸片肺高度减少了不确定性。
Errors in measuring chest X-ray (CXR) lung heights could contribute to the occurrence of size-mismatched lung transplant procedures. We first used Bland-Altman analysis for repeated measures to evaluate contributors to measurement error of chest X-ray lung height. We then applied error propagation theory to assess the impact of measurement error on size matching for lung transplantation. A total 387 chest X-rays from twenty-five donors and twenty-five recipients were measured by two raters. Individual standard deviation for lung height differences were independent of age, sex, donor vs. recipient, diagnostic group and race/ethnicity and all were pooled for analysis. Bias between raters was 0.27 cm (±0.03) and 0.22 cm (±0.06) for the right and left lung respectively. Within subject variability was the biggest contributor to error in measurement, 2.76 cm (±0.06) and 2.78 cm (±0.2) for the right and left lung height. A height difference of 4.4 cm or more (95% CI: ±4.2, ±4.6 cm) between the donor and the recipient right lung height has to be accepted to ensure matching for at least 95% of patients with the same true lung height. This difference decreases to ±1.1 cm (95% CI: ±0.9, ±1.3 cm) when the average from all available chest X-rays is used. The probability of matching a donor and a recipient decreases with increasing true lung height difference. Individual chest X-ray lung heights are imprecise for the purpose of size matching in lung transplantation. Averaging chest X-rays lung heights reduced uncertainty.
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影响因子：
6.2
作者：
Li, David;Weinkauf, Justin;Halloran, Kieran
通讯作者：
Halloran, Kieran
影响因子：
8.9
作者：
Chambers, Daniel C.;Cherikh, Wida S.;Stehlik, Josef
通讯作者：
Stehlik, Josef
影响因子：
8.9
作者：
Shigemura, Norihisa;Orhan, Yucel;Bermudez, Christian A.
通讯作者：
Bermudez, Christian A.
影响因子：
15.9
作者：
Hurtado, A;Fray, WW
通讯作者：
Fray, WW
影响因子：
4.6
作者：
Eberlein, Michael;Reed, Robert M.;Merlo, Christian A.
通讯作者：
Merlo, Christian A.