MOVEMENT OF MICROTUBULES BY SINGLE KINESIN MOLECULES
MOVEMENT OF MICROTUBULES BY SINGLE KINESIN MOLECULES
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DOI：
10.1038/342154a0
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发表时间：
1989-11-09
期刊：
影响因子：
64.8
通讯作者：
VALE, RD
中科院分区：
文献类型：
--
作者：
HOWARD, J;HUDSPETH, AJ;VALE, RD
驱动蛋白是利用ATP水解产生的能量沿沿着移动细胞器的马达蛋白。使用一种新的技术来测量单个驱动蛋白分子在体外产生的运动，结果表明，单个驱动蛋白分子可以移动微管几微米。提出了驱动蛋白产生力的机制的新信息。
Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles along microtubules. Using a new technique for measuring the movement produced in vitro by individual kinesin molecules, it is shown that a single kinesin molecule can move a microtubule for several micrometres. New information about the mechanism of force generation by kinesin is presented.