Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13.
Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13.
复制标题
编码 AP-2 转录因子的基因物理和遗传定位于小鼠 13 号染色体。
DOI：
10.1006/geno.1996.0037
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Williams,T
中科院分区：
文献类型：
--
作者：
Warren,G;Gordon,M;Siracusa,LD;Buchberg,AM;Williams,T
Transcription factors are a major determinant of developmental fate. The chromosomal localization of the genes encoding these proteins provides important information that can link them to known genetic abnormalities. Here, we report the mapping of the mouse gene for transcription factor AP-2, a protein that has been implicated in human oncogenesis. Using FISH, we have mapped the gene encoding the transcription factor AP-2,Tcfap2,to mouse Chromosome 13A5-B1. We have also extended this analysis by placingTcfap2on the mouse genetic map, and we discuss the candidate mouse mutations that map in the vicinity of this transcription factor.
