BTLA/HVEM Signaling: Milestones in Research and Role in Chronic Hepatitis B Virus Infection
BTLA/HVEM Signaling: Milestones in Research and Role in Chronic Hepatitis B Virus Infection
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DOI：
10.3389/fimmu.2019.00617
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Zhang Jiming
中科院分区：
文献类型：
--
作者：
Yu Xueping;Zheng Yijuan;Mao Richeng;Su Zhijun;Zhang Jiming
B- and T-lymphocyte attenuator (BTLA) is an immune-regulatory receptor, similar to.CTLA-4 and PD-1, and is mainly expressed on B-, T-, and all mature lymphocyte cells..Herpes virus entry mediator (HVEM)-BTLA plays a critical role in immune tolerance and.immune responses which are areas of intense research. However, themechanisms of the.BTLA and the BTLA/HVEM signaling pathway in human diseases remain unclear. This.review describes the research milestones of BTLA and HVEM in chronological order and.their role in chronic HBV infection
