Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction
Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction
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DOI：
10.1039/c2cc17566e
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发表时间：
2012-01-01
影响因子：
4.9
通讯作者：
Phillips, Scott T.
中科院分区：
文献类型：
--
作者：
Mohapatra, Hemakesh;Schmid, Kyle M.;Phillips, Scott T.
该通讯描述了三种小分子试剂，它们通过自催化反应放大检测事件的信号。从每种试剂中获得两个信号：(i) 二苯并富烯发色团和 (ii) 哌啶，可以使用 pH 指示剂染料将其可视化。这些试剂在钯的模型测定中得到了验证。
This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.