P3 Cognitive Potential in Cochlear Implant Users
P3 Cognitive Potential in Cochlear Implant Users
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DOI：
10.1055/s-0037-1613687
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发表时间：
2018-12-01
影响因子：
1.1
通讯作者：
Bento, Ricardo Ferreira
中科院分区：
文献类型：
--
作者：
Grasel, Signe;Greters, Mario;Bento, Ricardo Ferreira
P3认知诱发电位是指当受试者正确识别、评价和处理两种不同的听觉刺激时所记录的P3认知诱发电位。目的评价26例人工耳蜗植入者的P3诱发电位的潜伏期和波幅，并与年龄和教育程度相匹配的听力正常者进行比较。对26例语后聋人工耳蜗植入者的听觉皮层反应进行了记录结果人工耳蜗植入者语音识别成绩差者（G-组）与对照组（CG组）的P3潜伏期差异有统计学意义（P <0.05）。（p = 0.04），以及具有良好言语辨别力（G+）的G-和人工耳蜗植入者之间（p = 0.01）。我们发现CG和G+之间的P3潜伏期无显著差异。在这项研究中，所有G-患者耳聋由于脑膜炎，这表明，更高的听觉功能受损tower.Conclusion语后聋成人人工耳蜗植入者在G-组延长P3潜伏期相比，CG和人工耳蜗植入者在G+组。患者和对照组之间的振幅相似。所有G-受试者均因脑膜炎而耳聋。这些结果表明，脑膜炎可能有有害的影响，不仅对外周听觉系统，但对中央听觉处理以及。
Introduction The P3 cognitive evoked potential is recorded when a subject correctly identifies, evaluates and processes two different auditory stimuli.Objective to evaluate the latency and amplitude of the P3 evoked potential in 26 cochlear implant users with post-lingual deafness with good or poor speech recognition scores as compared with normal hearing subjects matched for age and educational level.Methods In this prospective cohort study, auditory cortical responses were recorded from 26 post-lingual deaf adult cochlear implant users (19 with good and 7 with poor speech recognition scores) and 26 control subjects.Results There was a significant difference in the P3 latency between cochlear implant users with poor speech recognition scores (G-) and their control group (CG) (p = 0.04), and between G-and cochlear implant users with good speech discrimination (G+) (p = 0.01). We found no significant difference in the P3 latency between the CG and G+. In this study, all G-patients had deafness due to meningitis, which suggests that higher auditory function was impaired too.Conclusion Post-lingual deaf adult cochlear implant users in the G-group had prolonged P3 latencies as compared with the CG and the cochlear implant users in the G+ group. The amplitudes were similar between patients and controls. All G-subjects were deaf due to meningitis. These findings suggest that meningitis may have deleterious effects not only on the peripheral auditory system but on the central auditory processing as well.