Incidence and clinical consequences of distal embolization on the coronary angiogram after percutaneous coronary intervention for ST-elevation myocardial infarction
Incidence and clinical consequences of distal embolization on the coronary angiogram after percutaneous coronary intervention for ST-elevation myocardial infarction
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DOI：
10.1093/eurheartj/ehp033
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发表时间：
2009-04-01
影响因子：
39.3
通讯作者：
Zijlstra, Felix
中科院分区：
文献类型：
--
作者：
Fokkema, Marieke L.;Vlaar, Pieter J.;Zijlstra, Felix
我们研究了ST段抬高型心肌梗死患者接受阿司匹林、肝素、氯吡格雷和糖蛋白-IIb/IIIa抑制剂治疗后直接经皮冠状动脉介入治疗（PCI）后血管造影可见远端栓塞（AVDE）的发生率和后遗症，作为TAPAS的一部分，AVDE是预定的次要终点。我们比较了经皮冠状动脉介入治疗（PCI）后有和无AVDE患者的血管造影和临床特征以及结局。AVDE在883例术后血管造影片中占6.3%。血管造影可见的远端栓塞与明显较差的结果相关，表现为较低的心肌发红等级、受损的ST段恢复和较高的酶水平（所有P
We investigated the incidence and sequelae of angiographically visible distal embolization (AVDE) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction patients treated with aspirin, heparin, clopidogrel, and glycoprotein-IIb/IIIa inhibitors.As part of TAPAS, AVDE was a predefined secondary endpoint. We compared angiographic and clinical characteristics, and outcomes of patients with and without AVDE after PCI. AVDE was present on 6.3% of 883 post-procedural angiograms. Angiographically visible distal embolization was associated with significantly worse outcomes, as expressed by lower myocardial blush grade, impaired ST-segment resolution, and higher enzyme levels (all P