Oral cancer incidence and mortality in China, 2011
Oral cancer incidence and mortality in China, 2011
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DOI：
10.3978/j.issn.1000-9604.2015.01.03
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发表时间：
2015-02-01
影响因子：
5.1
通讯作者：
Chen, Wanqing
中科院分区：
文献类型：
--
作者：
Zhang, Shao-Kai;Zheng, Rongshou;Chen, Wanqing
目的：了解2011年中国人群口腔癌的发病率和死亡率，为口腔癌的预防和研究提供有价值的数据。根据质量控制标准进行评价后，本研究接受了分布在28个省的177个基于人群的癌症登记处的数据，共覆盖175，310人，169人，占2011年全国总人口的13.01%。按地区、性别和年龄组计算发病率和死亡率。新病例和死亡人数是使用5岁特定癌症发病率/死亡率和相应人口估计的。结果：2000年中国口腔癌新发病例估计为39，450例，其中男性26，160例，女性13，290例。口腔癌的整体粗发病率为2.93/100，000。中国（ASR（CN））和世界（AS（wld））人群的年龄标准化率分别为2.22/10万和2.17/10万。在0-74岁的受试者中，累积发生率为0.25%。2011年中国口腔癌死亡人数估计为16,933人，其中男性11,794人，女性5,139人。总体粗死亡率为1.26/10万，占所有癌症死亡的0.80%。死亡率的ASR（CN）和ASR（wld）分别为0.90/10万和0.89/10万。在0-74岁受试者中，累积死亡率为0.10%。男性和城市地区口腔癌的发病率和死亡率明显高于女性和农村地区。结论：本研究结果对口腔癌的预防和研究具有重要意义。虽然我国口腔癌的疾病负担不高，但也必须引起重视。此外，口腔癌的一级和二级预防研究，尤其是高危人群的预防研究，还有待于进一步的研究。
Objective: To descript the incidence and mortality rates of oral cancer among Chinese population in 2011, and provide valuable data for oral cancer prevention and research.Methods: Data from 177 population-based cancer registries distributed in 28 provinces were accepted for this study after evaluation based on quality control criteria, covering a total of 175,310,169 populations and accounting for 13.01% of the overall national population in 2011. Incidence and mortality rates were calculated by area, gender and age groups. The numbers of new cases and deaths were estimated using the 5-year age-specific cancer incidence/mortality rates and the corresponding populations. The Chinese population in 2000 and World Segi's population were used for age-standardized rates.Results: The estimate of new cases diagnosed with oral cancer was 39,450 including 26,160 males and 13,290 females. The overall crude incidence rate for oral cancer was 2.93/100,000. The age-standardized rates by China (ASR(CN)) population and by World population (AS(wld)) were 2.22/100,000 and 2.17/100,000, respectively. Among subjects aged 0-74 years, the cumulative incidence rate was 0.25%. The estimated number of oral cancer deaths of China in 2011 was 16,933, including 11,794 males and 5,139 females. The overall crude mortality rate was 1.26/100,000, accounting for 0.80% of all cancer deaths. The ASR(CN) and ASR(wld) for mortality were 0.90/100,000 and 0.89/100,000, respectively. Among subjects aged 0-74 years, the cumulative mortality rate was 0.10%. The incidence and mortality rates of oral cancer were much higher in males and urban areas than in females and rural areas. In addition, the incidence and mortality rates were increased by the raising of ages.Conclusions: Results in the study may have important roles for oral cancer prevention and research. Although oral cancer burden of China is not high, we must pay attention to this malignancy as well. In addition, further researches need to be done for primary and secondary prevention research of oral cancer, especially for the high risk population.