Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives.
Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives.
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DOI：
10.1007/bf02982704
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发表时间：
2008-08
影响因子：
5.8
通讯作者：
Vellas, B.
中科院分区：
文献类型：
--
作者：
Rolland, Y.;Czerwinski, S.;van Kan, G. Abellan;Morley, J. E.;Cesari, M.;Onder, G.;Woo, J.;Baumgartner, R.;Pillard, F.;Boirie, Y.;Chumlea, W. M. C.;Vellas, B.
肌肉减少症是肌肉蛋白质质量的损失和肌肉功能的损失。它随着年龄的增长而发生，是脆弱发展的主要组成部分。目前的知识，其评估，病因，发病机制，后果和未来的前景报告在本审查。正在进行的和未来的肌肉减少症的临床试验可能会从根本上改变我们对老年人行动能力障碍的预防和治疗方法。
Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.