Predictors of neuropsychological impairment in alcoholics: antisocial versus nonantisocial subtypes.
Predictors of neuropsychological impairment in alcoholics: antisocial versus nonantisocial subtypes.
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酗酒者神经心理损伤的预测因素：反社会与非反社会亚型。
DOI：
10.1016/0306-4603(95)00035-6
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发表时间：
1996
影响因子：
4.4
通讯作者：
Longabaugh,R
中科院分区：
文献类型：
--
作者：
Waldstein,SR;Malloy,PF;Stout,R;Longabaugh,R
研究了22例反社会人格障碍（ASPD）酗酒者和84例非ASPD酗酒者的人口学特征、围产期/发育特征和获得性被试特征在决定神经心理（NP）表现中的作用。逐步多元回归分析结果显示，在反社会人格障碍被试中，较低的受教育程度、儿童时期的品行障碍症状、每日饮酒量是NP表现较差的预测因素。头部损伤史占解释方差的80% （p < 0.0001）。在非反人格障碍受试者中。NP表现通过自我报告的诊断为注意缺陷障碍、语言学习障碍和非语言学习障碍的病史来预测，占解释方差的24% （p < 0.0001）。这些结果表明，在ASPD和非ASPD酗酒者中存在可能不同的NP障碍终生路径。进一步探索酗酒亚组神经心理表现的多变量预测因素是有必要的。
The role of demographic, perinatal/developmental, and acquired subject characteristics in determining neuropsychological (NP) performance was investigated in 22 alcoholics with Antisocial Personality Disorder (ASPD) and 84 non-ASPD alcoholics. Results of stepwise multiple regression analyses revealed that in ASPD subjects, poor NP performance was predicted by less education, childhood symptoms of Conduct Disorder, drinks per drinking day. and history of head injury, accounting for 80% of the explained variance (p < .0001). In non-ASPD subjects. NP performance was predicted by self-reported history of diagnosed Attention Deficit Disorder, Verbal Learning Disability, and symptoms of Nonverbal Learning Disability, accounting for 24% of the explained variance (p < .0001). These results suggest the presence of potentially different lifelong paths to NP impairment among ASPD and non-ASPD alcoholics. Further exploration of the multivariate predictors of neuropsychological performance in subgroups of alcoholics is warranted.