Urinary corticosterone levels in mice in response to intraperitoneal injections with saline
Urinary corticosterone levels in mice in response to intraperitoneal injections with saline
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DOI：
10.1207/s15327604jaws0804_4
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发表时间：
2005-01-01
影响因子：
1.5
通讯作者：
Baumans, Vera
中科院分区：
文献类型：
--
作者：
Meijer, Margot K.;Lemmens, Arnoldina G.;Baumans, Vera
细化的概念是实验动物科学领域的一个重要问题。基于改进的研究旨在改善动物福利，增加实验结果的可靠性，并减少变异。为了寻求实验技术的改进，本研究探讨了尿皮质酮是否可以作为一种非侵入性的测量急性应激小鼠。
The concept of refinement is an important issue in the field of laboratory animal science. Refinement-based research aims to improve animal welfare, to increase the reliability of experimental outcome, and to diminish variation. In search of refinement of experimental techniques, this study investigated whether urinary corticosterone can be used as a noninvasive measure of acute stress in mice.