Quality assessment of the cortical bone of the human mandible
Quality assessment of the cortical bone of the human mandible
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DOI：
10.1016/s8756-3282(02)00921-3
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发表时间：
2003-01-01
期刊：
影响因子：
4.1
通讯作者：
Cuppone, M
中科院分区：
文献类型：
--
作者：
Lettry, S;Seedhom, BB;Cuppone, M
本研究首次同时研究了新鲜下颌骨的力学性能和计算机断层扫描（CT）数量的区域和方向变化，并探讨了两组数据之间的相关性，以期为牙种植体的设计者提供一种无创的方法来确定骨质量。使用三点弯曲试验的区域变化的杨氏模量的骨在人类下颌骨确定从5个新鲜标本的捐助者代表的患者需要牙种植体中的一些下颌骨是完全有齿的，一些部分，和一些完全无齿。虽然在我们测试的下颌骨中，模量分布的模式是明显的，但这些下颌骨确实具有各自的状态，它们自己的特性。我们还确定了下颌骨模量的方向变化，这是由于骨的各向异性性质。在我们的研究中获得的模量值远低于在唯一的其他已发表的研究中列出的那些值，该研究是在干燥的下颌骨上进行的。两项研究中模量数据的这些差异部分归因于骨状况的差异和两项研究中测试样本尺寸的差异。由于本研究中获得的模量值低于先前发表的值，因此作为植入物设计的基础更安全。一个弱的相关性被发现之间的模量值和CT数的下颌骨。这不足以从CT扫描中准确预测骨特性。因此，开发一种非侵入性方法来确定各种患者的骨质量仍然是研究人员面临的挑战。(C)2003 Elsevier Science（美国）。All rights reserved.
This study is the first to investigate simultaneously both the regional and the directional variations in mechanical properties and computed tomography (CT) numbers of the fresh mandible bone and to explore the correlation between the two sets of data with a view to provide a noninvasive method for determining the bone quality for designers of dental implants. Using a three-point bending test the regional variation of Young's modulus of bone in the human mandible was determined from five fresh specimens from donors representative of patients in need of dental implants in that some of the mandibles were fully dentulate, some partly so, and some fully edentulate. While a pattern of the modulus distribution was evident in the mandibles we tested, these mandibles did have, as a result of their respective states, their own peculiarities. We determined also the directional variations of the modulus for the mandible, which are due to the anisotropic nature of bone. The modulus values obtained in our study were much lower than those listed in the only other published study, which was conducted on dry mandibles. These differences in the modulus data from the two studies were attributed partly to the differences in condition of the bone and differences in the dimensions of specimens tested in the two studies. Because the values of the modulus obtained in this study are lower than those previously published, they would be safer as a basis for implant designs. A weak correlation was found between the modulus values and the CT number of the mandible. This would not be sufficient for accurate predictions of the bone properties from CT scans. The development of a noninvasive method for determining the bone quality in various patients thus remains a challenge for researchers. (C) 2003 Elsevier Science (USA). All rights reserved.