Complementary and alternative medicine use in patients before and after a cancer diagnosis
Complementary and alternative medicine use in patients before and after a cancer diagnosis
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DOI：
10.3747/co.25.3884
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发表时间：
2018-08-01
期刊：
影响因子：
2.6
通讯作者：
Want, D. A.
中科院分区：
文献类型：
--
作者：
Buckner, C. A.;Lafrenie, R. M.;Want, D. A.
癌症患者越来越多地寻求补充和替代医学（CAM），并且可能不愿意向他们的肿瘤治疗团队透露其用途。通常，CAM药物没有得到很好的研究，对它们与化疗、放疗或生物治疗的潜在相互作用以及它们与结果的相关性知之甚少。在目前的研究中，我们着手确定在安大略省北部癌症中心接受治疗的患者中CAM的使用率。方法在安大略省萨德伯里东北癌症中心（NECC）接受治疗的患者被要求完成一份匿名问卷来评估CAM的使用情况。还评估了诊断前与诊断后CAM使用的变化。结果北安大略省的患者在诊断前后均报告了显著的CAM使用情况。然而，作为CAM类型的一个功能，在癌症诊断后，CAM的使用大大增加。例如，癌症诊断后报告使用生物制品的患者人数从癌症诊断前的15.6%增加到51.8%。患者报告在诊断后使用替代医疗系统或精神治疗的变化要小得多。66%的受访者报告了维生素的使用情况，使用不同CAMS的数量与报告的维生素使用数量显著相关。结论：癌症诊断后，CAM的使用，特别是生物制品的使用显著增加。需要进一步的研究来检验使用辅助生殖激素对癌症治疗的有效性和安全性的影响。
Background Cancer patients are increasingly seeking out complementary and alternative medicine (CAM) and might be reluctant to disclose its use to their oncology treatment team. Often, CAM agents are not well studied, and little is known about their potential interactions with chemotherapy, radiation therapy, or biologic therapies, and their correlations with outcomes. In the present study, we set out to determine the rate of CAM use in patients receiving treatment at a Northern Ontario cancer centre.Methods Patients reporting for treatment at the Northeast Cancer Centre (NECC) in Sudbury, Ontario, were asked to complete an anonymous questionnaire to assess CAM use. Changes in CAM use before, compared with after, diagnosis were also assessed.Results Patients in Northern Ontario reported significant CAM use both before and after diagnosis. However, as a function of the CAM type, CAM use was greatly enhanced after cancer diagnosis. For example, the number of patients who reported use of biologic products increased to 51.8% after a cancer diagnosis from 15.6% before a cancer diagnosis. Patients reported much smaller changes in the use of alternative medical systems or spiritual therapy after diagnosis. Vitamin use was reported by 66% of respondents, and the number of different CAMS used correlated significantly with the reported number of vitamins used.Conclusions Use of CAM, particularly biologic products, increased significantly after a cancer diagnosis. Further studies are required to examine the effect of CAM use on the efficacy and safety of cancer therapies.