A single 24-hour urine collection is inadequate for the medical evaluation of nephrolithiasis
A single 24-hour urine collection is inadequate for the medical evaluation of nephrolithiasis
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DOI：
10.1016/s0022-5347(05)65163-4
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发表时间：
2002-04-01
影响因子：
6.6
通讯作者：
Coe, FL
中科院分区：
文献类型：
--
作者：
Parks, JH;Goldfisher, E;Coe, FL
目的：我们确定了一个单一的24小时尿液样本的充分性，以评估患者的医疗肾stoneprevention.Materials和方法：共459名患者从私人泌尿科的做法，专门治疗尿石症和683从一所大学的石头研究诊所提供2和3，24小时的尿液样本，分别。我们使用来自私人执业患者的样本1和2以及来自大学诊所患者的样本1和3进行分析，并通过相关系数和计算差异的平均差±标准差（SD）进行比较。尿危险因素进行了测量，通过标准的methods.Results：虽然尿值1和2的相关性是优秀的所有结石的危险因素，SD值的差异是足够大的，在1 SD的任何一侧0，其中包括68.8%的情况下，偶然尿1将离开尿2临床上重要的金额。这些偏离将足以误诊常见的代谢disorders.Conclusions：一个单一的24小时的样本是不足以评估患者的代谢治疗前预防结石，因为误诊是常见的，导致不适当的治疗。
Purpose: We determined the adequacy of a single 24-hour urine sample for evaluating patients for medical renal stone prevention.Materials and Methods: A total of 459 patients from a private urology practice specializing in the treatment of urolithiasis and 683 from a university stone research clinic provided 2 and 3, 24-hour urine samples, respectively. We used samples 1 and 2 from private practice patients, and I and 3 from university clinic patients for analysis, and compared each to the others by correlation coefficients and calculation of the mean difference plus or minus standard deviation (SD) of the difference. Urine risk factors were measured by standard methods.Results: Although the correlation of urine values 1 and 2 was excellent for all stone risk factors, SD values for the differences were large enough that within 1 SD on either side of 0, which included 68.8% of cases, by chance urine 1 would depart from urine 2 by clinically important amounts. These departures would be more than sufficient to misdiagnose common metabolic disorders.Conclusions: A single 24-hour sample is not sufficient for evaluating patients before metabolic treatment for stone prevention because misdiagnosis is common, leading to inappropriate treatment.