Alkylation of aldehydes with trialkylboranes in water
Alkylation of aldehydes with trialkylboranes in water
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DOI：
10.1002/adsc.200606136
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发表时间：
2006-08-01
影响因子：
5.4
通讯作者：
Shima, Koichiro
中科院分区：
文献类型：
--
作者：
Hirano, Koji;Yorimitsu, Hideki;Shima, Koichiro
水能够使醛与三烷基硼烷在镍催化下烷基化而无需添加碱。由硼烷-二甲基硫醚和末端烯烃通过硼氢化制备的三烷基硼烷以及可商购的三烷基硼烷可用于该反应。该反应将通过η（2）-配位的镍配合物与醛作为关键中间体进行。
Water enables the alkylation of aldehydes with trialkylboranes under nickel catalysis without the addition of a base. Trialkylboranes prepared from borane-dimethyl sulfide and terminal olefins via hydroboration as well as commercially available trialkylboranes could be employed for the reaction. The reaction would proceed via eta(2)-coordinated nickel complexes with aldehydes as the key intermediates.