Subject reactivity effects and alcohol treatment outcome research
Subject reactivity effects and alcohol treatment outcome research
复制标题
DOI：
10.15288/jsa.2000.61.787
复制
发表时间：
2000-11-01
期刊：
影响因子：
--
通讯作者：
Maisto, SA
中科院分区：
文献类型：
--
作者：
Clifford, PR;Maisto, SA
目的：关于影响临床结果的酒精治疗研究方案的归因已持续超过 25 年。尽管精心设计的酒精治疗结果研究通常涉及频繁且通常全面的研究评估方案，但很少有程序来控制或解释受试者对研究方案可能的反应。本文为研究方案和治疗结果之间的关系提供了理论基础。方法：文章回顾了相关的酒精治疗结果文献，并提出了有关受试者反应影响和酒精治疗结果研究评估方案的“证据权重”。此外，框架（反馈、责任、建议、菜单、同理心和自我效能）模型与自我调节理论相结合，为研究评估方案如何促进临床相关的行为改变提供了理论解释。结果：研究人员的归因、实证调查和理论考虑都提供了与受试者对研究评估方案的反应一致的证据。结论：针对酒精治疗结果研究中收集的数据的解释、潜在受试者反应性混杂变量的控制以及未来研究的方向提出了建议。
Objective: Attributions regarding alcohol treatment research protocols influencing clinical outcomes have persisted for more than 25 years. Although well-designed alcohol treatment outcome studies typically involve frequent, and often comprehensive, research assessment protocols, procedures are seldom in place to control or account for possible subject reactivity to the research protocol. This article presents a theoretical basis for a relationship between research protocols and treatment outcomes. Method: The article reviews the relevant alcohol treatment outcome literature and presents a "weight of evidence" regarding subject reactivity effects and alcohol treatment outcome research assessment protocols. Also, the FRAMES (feedback, responsibility, advice, menu, empathy and self-efficacy) model was coupled with self-regulation theory to provide a theoretical explanation of how research assessment protocols might contribute to clinically relevant behavioral change. Results: Researcher attributions, empirical investigations and theoretical considerations all provide evidence that is consistent with the existence of subject reactivity to research assessment protocols. Conclusions: Recommendations are made regarding interpretation of data collected as part of an alcohol treatment outcome study, control of potential subject reactivity confounding variables and directions for future research.