A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance.
A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance.
复制标题
YB-1在肿瘤发生、转移及耐药中的作用综述
DOI:
10.1016/j.cellsig.2021.110073
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发表时间:
2021-09
影响因子:
4.8
通讯作者:
Sossey-Alaoui K
中科院分区:
文献类型:
--
作者:
Alkrekshi A;Wang W;Rana PS;Markovic V;Sossey-Alaoui K
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain protein family with multifunctional properties both in the cytoplasm and inside the nucleus. YB-1 is also involved in various cellular functions, including regulation of transcription, mRNA stability, and splicing. Recent studies have associated YB-1 with the regulation of the malignant phenotypes in several tumor types. In this review article, we provide an in-depth and expansive review of the literature pertaining to the multiple physiological functions of YB-1. We will also review the role of YB-1 in cancer development, progression, metastasis, and drug resistance in various malignancies, with more weight on literature published in the last decade. The methodology included querying databases PubMed, Embase, and Google Scholar for Y box binding protein 1, YB-1, YBX1, and Y-box-1.
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DOI:
10.1038/nrc.2017.99
发表时间:
2018-01
期刊:
Nature reviews. Cancer
影响因子:
--
作者:
Anastasiadou E;Jacob LS;Slack FJ
通讯作者:
Slack FJ
影响因子:
8
作者:
Astanehe, A.;Finkbeiner, M. R.;Dunn, S. E.
通讯作者:
Dunn, S. E.
影响因子:
8
作者:
Davies AH;Barrett I;Pambid MR;Hu K;Stratford AL;Freeman S;Berquin IM;Pelech S;Hieter P;Maxwell C;Dunn SE
通讯作者:
Dunn SE
影响因子:
8.4
作者:
Basaki, Yuji;Taguchi, Ken-ichi;Kuwano, Michihiko
通讯作者:
Kuwano, Michihiko
影响因子:
16.8
作者:
Dutertre, Martin;Sanchez, Gabriel;Auboeuf, Didier
通讯作者:
Auboeuf, Didier