MicroRNAs in Rice Innate Immunity.
MicroRNAs in Rice Innate Immunity.
复制标题
水稻先天免疫中的microRNA。
DOI：
10.1186/s12284-016-0078-5
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发表时间：
2016-12
期刊：
影响因子：
--
通讯作者：
San Segundo B
中科院分区：
文献类型：
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作者：
Baldrich P;San Segundo B
MicroRNAs （miRNAs）是一种短的非编码调控rna，在大多数真核生物中指导基因沉默。它们通过触发序列特异性切割或靶转录物的翻译抑制来调节基因表达。众所周知，植物mirna在广泛的发育过程中发挥着重要作用。越来越多的证据也支持miRNA水平的调节在重新编程植物对非生物胁迫（干旱、寒冷、盐度和营养缺乏）和生物胁迫（抗菌抗性）的反应中起重要作用。这些研究大多是在模式植物拟南芥中进行的。在过去的几年里，高通量测序技术的采用在揭示多种miRNA的同时，也为植物中的miRNA分析做出了重大贡献。然而，尽管大量的水稻mirna已被证明受到病原体感染的调节，但它们的生物学功能在很大程度上仍然未知。本文综述了mirna在水稻免疫中的作用，并讨论了其在水稻生物技术中的潜在应用。更好地了解控制水稻免疫的miRNA物种可能会导致实际的生物技术应用，从而制定适当的水稻保护策略。
MicroRNAs (miRNAs) are short regulatory non-coding RNAs that guide gene silencing in most eukaryotes. They regulate gene expression by triggering sequence-specific cleavage or translational repression of target transcripts. Plant miRNAs are known to play important roles in a wide range of developmental processes. Increasing evidence also supports that the modulation of miRNA levels plays an important role in reprogramming plant responses to abiotic stress (drought, cold, salinity and nutrient deficiency) and biotic stress (antibacterial resistance). Most of these studies were carried out in the model plant Arabidopsis thaliana. During the last years, the adoption of high-throughput sequencing technologies has significantly contributed to uncover multiple miRNAs while allowing miRNA profiling in plants. However, although a plethora of rice miRNAs have been shown to be regulated by pathogen infection, the biological function remains largely unknown for most of them. In this review, we summarize our current understanding on the contribution of miRNAs to rice immunity and discuss their potential applications in rice biotechnology. A better understanding of the miRNA species controlling rice immunity may lead to practical biotechnological applications leading to the development of appropriate strategies for rice protection.