Uniform design and its applications in chemistry and chemical engineering
Uniform design and its applications in chemistry and chemical engineering
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DOI：
10.1016/s0169-7439(01)00139-3
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发表时间：
2001-09-28
影响因子：
3.9
通讯作者：
Xu, QS
中科院分区：
文献类型：
--
作者：
Liang, YZ;Fang, KT;Xu, QS
实验设计在化学计量学中非常重要，因为直到现在，化学本质上仍然是一个强烈依赖于化学实验的科学领域。因此，长期以来，化学家们一直试图利用统计学中发展起来的实验设计技术来改进实验工作。综述并比较了三种主要的实验设计方法，即析因设计（包括部分析因设计和正交设计）、D-最优设计和均匀设计，以及它们在化学化工中的应用，并着重介绍了均匀设计的特点。空间填充的均匀性是均匀设计最重要、最本质的特征。基于这一特点，其成本效益，鲁棒性和灵活性使其在化学和化学工程领域非常有用。自20世纪80年代以来，我国在纺织工业、制药工业、发酵工业等领域不断有应用均匀设计改进技术的成功实例。近年来，均匀设计在化学研究中的应用实例表明，均匀设计是一种很有前途的实验设计方法。(C)2001 Elsevier Science B. V.保留所有权利。
Experimental designs are very important in chemometrics, since chemistry, until now, is still essentially a field of science strongly dependent on chemical experiments. So, for a long time, chemists have been trying to use the techniques of experimental design developed in statistics to improve experimental works. Three major methods of experimental design, such as factorial design including fractional factorial design and orthogonal design (OD), D-optimal design and uniform design (UD), and their applications in chemistry and chemical engineering are reviewed and compared, The features of uniform design are especially addressed. Uniformity of space filling is the most important and essential feature of the uniform design. Based on this feature, its cost-efficiency, robustness and flexibility make it very useful in the fields of chemistry and chemical engineering. Examples of successful applications of uniform design on improving technologies of various fields such as textile industry, pharmaceuticals, fermentation industry and others have been consistently reported in China since the 1980s. More recently, several various cases applying uniform design to chemical researches showed that the uniform design is indeed a very promising and powerful experimental design method. (C) 2001 Elsevier Science B.V. All rights reserved.