SUBARACHNOID HEMORRHAGE IN THE RAT - ANGIOGRAPHY AND FLUORESCENCE MICROSCOPY OF THE MAJOR CEREBRAL-ARTERIES
SUBARACHNOID HEMORRHAGE IN THE RAT - ANGIOGRAPHY AND FLUORESCENCE MICROSCOPY OF THE MAJOR CEREBRAL-ARTERIES
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DOI：
10.1161/01.str.16.4.595
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发表时间：
1985-01-01
期刊：
影响因子：
8.3
通讯作者：
SVENDGAARD, NA
中科院分区：
文献类型：
--
作者：
DELGADO, TJ;BRISMAR, J;SVENDGAARD, NA
大鼠蛛网膜下腔出血（SAH）是通过先前植入的连接到枕大池的导管注射血液产生的。重复的椎基底动脉血管造影检查显示双相性血管痉挛，脑池注血后10分钟出现最大急性痉挛，2天后出现最大晚期痉挛。荧光显微镜检查的主要脑动脉在第2天SAH后发现荧光强度和组织化学可见的交感神经末梢的数量减少。
A subarachnoid hemorrhage (SAH) in the rat was produced by the injection of blood via a previously implanted catheter connected to the cisterna magna. Repeated angiographical examinations of the vertebro-basilar arteries revealed a biphasic vasospasm with a maximal acute spasm at 10 min and a maximal late spasm at 2 days after cisternal blood injection. Fluorescence microscopical examination of the major cerebral arteries at day 2 after the SAH revealed a reduction in the fluorescence intensity and in the number of histochemically visible sympathetic nerve terminals.