Prognostic significance of red cell distribution width in acute mesenteric ischemia
Prognostic significance of red cell distribution width in acute mesenteric ischemia
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DOI：
10.1177/0267659114534289
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发表时间：
2015-03-01
期刊：
影响因子：
1.2
通讯作者：
Tez, M.
中科院分区：
文献类型：
--
作者：
Bilgic, I.;Dolu, F.;Tez, M.
目的：急性肠系膜缺血（AMI）是一种罕见的，但复杂的，危及生命的疾病。鉴于这种不良结局，估计死亡率将有助于医生、患者及其家属做出决策。红细胞分布宽度（RDW）反映全身炎症。RDW是一个显着的预后指标，用于确定在广泛的临床表现的死亡率的风险。本研究的目的是探讨RDW与AMI患者死亡率之间的关系。方法：回顾性分析术前诊断为AMI的剖腹手术患者的病历。结果：RDW对死亡率具有良好的判别力（曲线下面积= 0.713; 95%可信区间0.584-0.841）。RDW的截止值为14.85，死亡率可以正确预测在大约70%的cases.Conclusions：增加RDW在入院时是AMI患者的坏死程度和死亡率的预测因子。需要进一步的前瞻性研究来更准确地评估RDW在这些患者中的重要性。
Objective: Acute mesenteric ischemia (AMI) is an infrequent, but complicated, life-threatening condition. Given this poor outcome, an estimation of mortality would aid in decision making for physicians, patients and their families. Red cell distribution width (RDW) is reflective of systemic inflammation. RDW is a remarkable prognostic marker for determining the risk of mortality in a wide range of clinical manifestations. The objective of this study was to investigate the association between RDW and mortality in patients with AMI.Methods: The medical records of patients who underwent laparotomy with a preoperative diagnosis of AMI were reviewed retrospectively. Primary outcome variable was the hospital mortality rate.Results: Estimating the receiver operating characteristic area under the curve showed that RDW has good discriminative power for mortality (area under the curve = 0.713; 95% confidence interval, 0.584-0.841). With a cut-off value of 14.85 for RDW, mortality could be correctly predicted in approximately 70% of cases.Conclusions: Increased RDW at admission was a predictor of the extent of necrosis and mortality in AMI patients. Further prospective studies are necessary to more accurately assess the importance of RDW in these patients.