A SUGGESTED COLUMNAR CELL MORPHOLOGICAL EQUIVALENT OF SQUAMOUS CARCINOMA INSITU WITH EARLY STROMAL INVASION
A SUGGESTED COLUMNAR CELL MORPHOLOGICAL EQUIVALENT OF SQUAMOUS CARCINOMA INSITU WITH EARLY STROMAL INVASION
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DOI：
10.1097/00004347-198909000-00006
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发表时间：
1989-09-01
影响因子：
2.4
通讯作者：
BRADGATE, MG
中科院分区：
文献类型：
--
作者：
ROLLASON, TP;CULLIMORE, J;BRADGATE, MG
宫颈原位鳞状细胞癌伴早期间质浸润最近被定义为一种严格的组织学实体。两例广泛的经典原位腺癌的子宫颈和一个非常早期的浸润性腺癌的报告，显示病灶无法区分鳞状早期间质浸润直接产生明确的腺原位恶性病灶。这一发现进一步支持了宫颈腺上皮内瘤变和鳞状上皮内瘤变密切相关的理论，可能共同起源于柱状下储备细胞。
Cervical squamous carcinoma in situ with early stromal invasion has recently been defined as a strict histologic entity. Two cases of extensive classical adenocarcinoma in situ of the uterine cervix and one of very early invasive adenocarcinoma are reported that showed foci indistinguishable from squamous early stromal invasion arising directly from unequivocally glandular in situ malignant foci. This finding is further evidence in support of the theory that glandular and squamous intraepithelial neoplasia in the cervix are closely related conditions, possibly with a common origin in the subcolumnar reserve cell.